CDC - Scabies - Resources for Health Professionals - Medications.Permethrin (Topical Route) Proper Use - Mayo Clinic
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Elimite (permethrin) dose, indications, adverse effects, interactions from localhost.Permethrin Topical: MedlinePlus Drug Information |
- Permethrin 5 cream (elimite®)
- Permethrin 5 cream (elimite®)
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. All rights reserved. Retreatment 2 weeks after the initial treatment regimen can be considered for those persons who are still symptomatic or when live mites are observed.
Use of an alternative regimen is recommended for those persons who do not respond initially to the recommended treatment. Scabies rarely infests the scalp of adults, although the hairline, neck, temple, and forehead may be infested in geriatric patients. Usually 30 grams is sufficient for the average adult. Wash cream off after 8 to 14 hours. One application is generally curative. Although pruritus may persist after treatment, this is rarely a sign of treatment failure and is not an indication for retreatment.
Retreatment is indicated if living mites persist after 7 to 14 days of initial treatment. Specific guidelines for dosage adjustments in hepatic impairment are not available; it appears that no dosage adjustments are needed. Specific guidelines for dosage adjustments in renal impairment are not available; it appears that no dosage adjustments are needed.
Elimite topical cream: For the treatment of scabies, thoroughly massage cream into the skin from the head to the soles of the feet. Remove by washing after 8—14 hours. Nix Creme Rinse: Shake well before using. For the treatment of head lice, apply a sufficient amount to saturate the hair and scalp, especially behind the ears and on the nape of the neck. Leave on hair for 10 minutes. Use permethrin with caution in patients with hypersensitivity to other synthetic pyrethroids or pyrethrins, or to chrysanthemums.
Many veterinary or household insecticides contain permethrin or other synthetic pyrethroids. Thus, permethrin should be used with caution in patients sensitive to these insecticides. In cases of pediculosis capitis, self-medication of permethrin is not recommended if infestation of the eyebrows or eyelashes occurs. A physician should be consulted in these situations. Permethrin was not mutagenic when evaluated in several in vitro and in vivo genetic toxicity studies.
Permethrin-containing products are for external use only. These items should be washed in very hot water or dry-cleaned. You should also wash combs, brushes, hairs clips and other personal care items in hot water. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Permethrin may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture not in the bathroom. It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. If someone swallows permethrin, call your local poison control center at If the victim has collapsed or is not breathing, call local emergency services at Do not let anyone else use your permethrin cream.
Your prescription for permethrin cream is probably not refillable. If you feel you need additional treatment, call your doctor. Lice are generally spread by close head-to-head contact or from items that come in contact with your head.
Do not share combs, brushes, towels, pillows, hats, helmets, headphones, scarves, or hair accessories. Be sure to check everyone in your immediate family for head lice if another family member is being treated for lice. If you have scabies, tell your doctor if you have a sexual partner. This person should also be treated. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements.
You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies. Permethrin Topical pronounced as per meth' rin. Why is this medication prescribed? How should this medicine be used? Other uses for this medicine What special precautions should I follow? What special dietary instructions should I follow?
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Leave on hair for 10 minutes but no longer. Then, rinse thoroughly with water. If live lice are seen 7 days or more after the first application, a second treatment should be given. Patients should be evaluated 1 week after therapy and retreatment may be necessary. In epidemic settings, a second prophylactic application is recommended 2 weeks after the first since the life cycle of a head louse is approximately 4 weeks.
Retreatment 2 weeks after the initial treatment regimen can be considered for those persons who are still symptomatic or when live mites are observed. Use of an alternative regimen is recommended for those persons who do not respond initially to the recommended treatment. Scabies rarely infests the scalp of adults, although the hairline, neck, temple, and forehead may be infested in geriatric patients.
Usually 30 grams is sufficient for the average adult. Wash cream off after 8 to 14 hours. One application is generally curative. Although pruritus may persist after treatment, this is rarely a sign of treatment failure and is not an indication for retreatment.
Retreatment is indicated if living mites persist after 7 to 14 days of initial treatment. Specific guidelines for dosage adjustments in hepatic impairment are not available; it appears that no dosage adjustments are needed. Specific guidelines for dosage adjustments in renal impairment are not available; it appears that no dosage adjustments are needed. Elimite topical cream: For the treatment of scabies, thoroughly massage cream into the skin from the head to the soles of the feet.
Remove by washing after 8—14 hours. Nix Creme Rinse: Shake well before using. For the treatment of head lice, apply a sufficient amount to saturate the hair and scalp, especially behind the ears and on the nape of the neck.
Leave on hair for 10 minutes. Use permethrin with caution in patients with hypersensitivity to other synthetic pyrethroids or pyrethrins, or to chrysanthemums. Many veterinary or household insecticides contain permethrin or other synthetic pyrethroids. Thus, permethrin should be used with caution in patients sensitive to these insecticides. In cases of pediculosis capitis, self-medication of permethrin is not recommended if infestation of the eyebrows or eyelashes occurs.
A physician should be consulted in these situations. Permethrin was not mutagenic when evaluated in several in vitro and in vivo genetic toxicity studies. Permethrin-containing products are for external use only. In the event of ocular exposure, immediately flush eye with water. Safe and effective use of permethrin has not been established in neonates or infants less than 2 months of age.
Permethrin is classified as pregnancy category B. Reproductive studies in animals revealed no evidence of impaired fertility or harm to the fetus. However, there are no adequate and well-controlled studies in pregnant women. Thus, permethrin should be used during pregnancy only if clearly needed. It is not known if permethrin is excreted in human milk. However, absorption of permethrin from the skin is minimal, and it is rapidly metabolized to inactive metabolites.
Guidelines recommend permethrin for use in breast-feeding patients with lice and scabies. Consider the benefits of breast-feeding, the risk of potential infant drug exposure, and the risk of an untreated or inadequately treated condition. If a breast-feeding infant experiences an adverse effect related to a maternally administered drug, healthcare providers are encouraged to report the adverse effect to the FDA.
Mechanism of Action: Permethrin is active against a broad range of pests, including lice, ticks, fleas, mites, and other arthropods. Permethrin acts on the nerve cell membrane to disrupt the sodium channel current that regulates the polarization of the membrane. This results in delayed repolarization and subsequent paralysis and death of the parasites.
Permethrin exhibits residual ovicidal activity after rinsing. Permethrin is applied topically. The drug is rapidly metabolized by ester hydrolysis to inactive metabolites which are excreted primarily in urine. PDR Search. Required field.
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Related Drug Information Drug Summary. NOTE: For proper treatment of pediculosis, nits eggs should be removed with a nit comb. Also, all personal headgear, scarfs, coats, and bed linen should be disinfected by machine washing in hot water and drying using the hot cycle of a dryer for at least 20 minutes. Personal articles that cannot be washed may be dry-cleaned, sealed in a plastic bag for 4 weeks, or sprayed with a product specifically designed for this purpose. Personal combs and brushes may be disinfected by soaking in hot water above degrees F for 5 to 10 minutes.
For the treatment of pediculosis capitis head lice infestation due to Pediculus capitis. Topical dosage lotion. Infants, Children, and Adolescents 2 months to 17 years. Topical dosage cream. For pediculosis prophylaxis. For the treatment of scabies infection. Other Topical Formulations.
Topical Route. Back to top.
This medication is used to treat scabies, a condition caused by tiny insects called mites that infest and irritate your skin. Permethrin belongs to a class. Permethrin 5% w/w Cream is indicated for the treatment of scabies. Posology and method of administration. Permethrin 5% w/w Cream is suitable for adults. permethrin. Drug Summary How Supplied. Acticin/Elimite/Permethrin Topical Cream: 5% Nix Lice Killing Creme Rinse Topical Lotion: 1%. ELIMITE™ (permethrin) 5% Cream is a topical scabicidal agent for the treatment of infestation with Sarcoptesscabiei (scabies). Permethrin is used to treat scabies ('mites that attach themselves to the skin) in adults and children 2 months of age and older. Use permethrin exactly as directed. Tell your doctor if any of these symptoms are severe or do not go away: itching of skin or scalp area redness of skin or scalp area numbness or tingling of the skin rash Some side effects can be serious. Guidelines recommend permethrin for use in breast-feeding patients with lice and scabies.Drug information provided by: IBM Micromedex. Keep this medicine away from the eyes. If you accidentally get some in your eyes, flush them thoroughly with water at once. Permethrin lotion which is used to treat lice, comes in a container that holds only one treatment.
Use as much of the medicine as you need and discard any remaining lotion properly. Head lice can be easily transferred from one person to another by direct contact with clothing, hats, scarves, bedding, towels, washcloths, hairbrushes and combs, or hairs from infected persons.
Therefore, all members of your household should be examined for head lice and should receive treatment if they are found to be infected. If you have any questions about this, check with your doctor. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.
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