Looking for: Taking Benadryl With Hydrocodone And Prednisone.Benadryl With Synthroid And Prednisone Click here Benadryl with prednisone - There is no known drug interaction between diphenhydramine (the active ingredient in Benadryl and Sominex) and prednisone. They are considered. Benadryl and prednisone should be taken together with dinner. Foods allergy tests include amyl nitrite, butyl nitrite or nitrites may be more sensitive to lower. ❿ For Hives, A New Study Suggests Many Can Skip The Steroids | WBUR News Answered by Dr. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. If you are a Mayo Clinic patient, this could include protected health information. If you are taking Benadryl simply as a sleep aid, be sure to take it only in the evening, at least 4 to 6 hours after your last dose of hydrocodone to reduce the risk of additive sedation and serious side effects. Fortunately, as