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Topical Treatment of Facial Seborrheic Dermatitis: A Systematic Review - Background 













































   

 

Mometasone for skin – steroid creams used to treat eczema and psoriasis - NHS.Treatment of Seborrheic Dermatitis | AAFP



 

Ointments are thicker and greasier, and are better for dry or flaky areas of skin. The amount of cream or ointment you need to use is sometimes measured in fingertip units. This is the amount you can squeeze onto the end of your finger. For children, the right amount of cream or ointment depends on their age. A doctor or pharmacist can advise you. Skin creams can dry onto your clothes and bedding.

This makes them more likely to catch fire. Avoid naked flames. If you need to use a dressing, like a bandage or plaster, wait at least 10 minutes after putting mometasone on. If you're treating a child, do not cover the cream or ointment with dressings or bandages.

This can cause more medicine to pass through the skin and into the bloodstream, leading to a higher chance of side effects. If your doctor has prescribed it to treat very severe nappy rash, ask them how much to use and how long to use it for.

Once your skin starts getting better, do not stop using mometasone suddenly. Speak to your doctor, who might tell you to gradually reduce your dose or give you a milder steroid cream or ointment to use until you stop completely. Most people only need to use mometasone skin treatments for a short time.

Stop as soon as your skin is better. You will usually only use it for a few days. Children must not use mometasone skin treatments for more than 5 days, unless their doctor says to use it for longer.

Only use the cream or ointment for longer than 5 days if your doctor tells you to. Speak to your doctor if your skin gets worse or does not get better within 14 days of using mometasone skin treatments. If you forget to use your mometasone, do not worry.

In this case, skip the missed dose and apply the next one at the usual time. Mometasone skin products are unlikely to cause any side effects if you follow the instructions.

Some people get a burning or stinging feeling for a few minutes when they put mometasone on their skin.

Ask your doctor if you need to carry a steroid emergency card. Serious side effects are rare. Using mometasone for a long time can make your skin thinner or cause stretch marks. Stretch marks are likely to be permanent, but they usually fade over time. In very rare cases, using mometasone for a long time can slow down the normal growth of children and teenagers.

Your child's doctor will monitor their height and weight carefully for as long as they're using this medicine. This will help them to notice if your child's growth is being affected and change their treatment if needed. Even if your child's growth slows down, it does not seem to have much effect on their overall adult height. Talk to your doctor if you're worried.

They will be able to explain the benefits and risks of your child using mometasone. It happens rarely but it is possible to have a serious allergic reaction anaphylaxis to mometasone. These are not all the side effects of mometasone. For a full list see the leaflet inside your medicines packet.

Mometasone skin treatments are not normally recommended if you're pregnant. Only use mometasone if your doctor or dermatologist skin specialist prescribes it and is supervising your treatment. They will be able to explain the benefits and risks of using mometasone. If you're using mometasone on your breasts, wash off any cream or ointment from your breasts, then wash your hands before feeding your baby. It's usually better to use cream rather than ointment when breastfeeding, as it's easier to wash off.

For more information about how mometasone for skin might affect you and your baby during pregnancy, read this leaflet about steroid creams and ointments on the Best Use of Medicines in Pregnancy BUMPs website. Other medicines are unlikely to affect the way mometasone skin treatments work. There's very little information about taking herbal remedies and supplements while using mometasone. Ask a pharmacist for advice.

Tell your doctor or pharmacist if you're taking any other medicines, including herbal medicines, vitamins or supplements. Mometasone is a steroid also called a corticosteroid. Steroids help to reduce swelling inflammation in the skin and other parts of the body. Skin gets inflamed when an allergic reaction or irritation causes chemicals to be released in the skin.

These make your blood vessels widen and your irritated skin becomes red, swollen, itchy and painful. Why some persons develop seborrheic dermatitis and others do not is unclear. The colonization rate of involved skin by this organism may be lower than that of uninvolved skin. Genetic and environmental factors, as well as other comorbid diseases, may predispose specific populations to the development of seborrheic dermatitis. Although seborrheic dermatitis affects only 3 percent of the general population, the incidence in persons with acquired immunodeficiency syndrome may be as high as 85 percent.

The exact mechanism whereby human immunodeficiency virus infection promotes an atypical and explosive onset of seborrheic dermatitis and other common inflammatory skin disorders is unknown, but many factors have been explored, including CD4-positive T lymphocyte counts, 5 P. Persons with central nervous system disorders Parkinson's disease, cranial nerve palsies, major truncal paralyses also appear to be prone to the development of seborrheic dermatitis, tend to develop more extensive disease and are frequently refractory to treatment.

It has been postulated that seborrheic dermatitis in these patients is a result of increased pooling of sebum caused by immobility. This increased sebum pool permits growth of P. Seborrheic dermatitis typically affects areas of the skin where sebaceous glands appear in high frequency and are most active.

The distribution is classically symmetric, and common sites of involvement are the hairy areas of the head, including the scalp Figure 1 , the scalp margin Figure 2 , eyebrows, eyelashes, mustache and beard. Other common sites are the forehead Figure 3 , the nasolabial folds Figure 4 , the external ear canals Figure 5 and the postauricular creases.

Seborrhea of the trunk may appear in the presternal area Figure 6 and in the body folds, including the axillae, navel, groin, and in the inframammary and anogenital areas. Figure 7 illustrates the typically symmetric distribution of seborrheic dermatitis.

One of the characteristics of seborrheic dermatitis is dandruff, characterized by a fine, powdery white scale on the scalp. Many patients complain of the scalp itching with dandruff, and because they think that the scale arises from dry skin, they decrease the frequency of shampooing, which allows further scale accumulation. Inflammation then occurs and their symptoms worsen. More severe seborrheic dermatitis is characterized by erythematous plaques frequently associated with powdery or greasy scale in the scalp Figure 8 , behind the ears Figure 9 and elsewhere in the distribution described above.

Besides an itchy scalp, patients may complain of a burning sensation in facial areas affected by seborrhea. Seborrhea frequently becomes apparent when men grow mustaches or beards and disappears when the facial hair is removed. If left untreated, the scale may become thick, yellow and greasy and, occasionally, secondary bacterial infection may occur.

Seborrheic dermatitis is more common in men than in women, probably because sebaceous gland activity is under androgen control.

Hygiene issues play a key role in controlling seborrheic dermatitis. Frequent cleansing with soap removes oils from affected areas and improves seborrhea. Patients should be counseled that good hygiene must be a lifelong commitment.

Outdoor recreation, especially during summer, will also improve seborrhea, although caution should be taken to avoid sun damage. Pharmacologic treatment options for seborrheic dermatitis include antifungal preparations selenium sulfide, pyrithione zinc, azole agents, sodium sulfacetamide and topical terbinafine that decrease colonization by lipophilic yeast and anti-inflammatory agents topical steroids.

Suggested products are listed in Table 1. For severe disease, keratolytics such as salicylic acid or coal tar preparations may be used to remove dense scale; then topical steroids may be applied.

Other options for removing adherent scale involve applying any of a variety of oils peanut, olive or mineral to soften the scale overnight, followed by use of a detergent or coal tar shampoo. As a last resort in refractory disease, sebosuppressive agents such as isotretinoin Accutane may be used to reduce sebaceous gland activity. Many cases of seborrheic dermatitis are effectively treated by shampooing daily or every other day with antidandruff shampoos containing 2.

Alternatively, ketoconazole shampoo may be used. A moisturizing shampoo may be used afterward to prevent dessication of the hair. After the disease is under control, the frequency of shampooing with medicated shampoos may be decreased to twice weekly or as needed. Topical terbinafine solution, 1 percent, has also been shown to be effective in the treatment of scalp seborrhea.

If the scalp is covered with diffuse, dense scale, the scale may first be removed by applying warm mineral oil or olive oil to the scalp and washing several hours later with a detergent such as a dishwashing liquid or a tar shampoo.

Extensive scale with associated inflammation may be treated by moistening the scalp and then applying fluocinolone acetonide, 0. This treatment may be done nightly until the inflammation clears and then decreased to one to three times weekly as needed.

Pimecrolimus, the focus of seven of the 32 eligible studies, was the most commonly studied topical treatment. Ciclopirox olamine, ketoconazole, lithium gluconate and succinate , and tacrolimus are also strongly recommended level A recommendations topical treatments for facial SD, as they are consistently effective across high-quality trials randomized controlled trials. Abstract Background: Facial seborrheic dermatitis SD , a chronic inflammatory skin condition, can impact quality of life, and relapses can be frequent.

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Back to Medicines A to Z. Mometasone skin treatments are used to treat itching, swollen and irritated skin. They can help with different types of eczema including atopic dermatitis and seborrheic dermatitis and psoriasis. Mometasone skin treatments are available on prescription only.

They come as:. They are stronger than some other treatments. Mometasone is usually prescribed when milder steroids, like hydrocortisonehave not worked. Mometasone is a type of medicine known as a steroid also called a corticosteroid. This is not the same as an anabolic steroid. Most adults and children aged 2 years and older can use mometasone skin treatments. Mometasone may not be suitable for some people.

Tell a doctor or pharmacist before using it if you :. Always follow the instructions from a pharmacist, doctor or the leaflet that comes with your medicine.

Creams are better for skin that is moist and weepy. Ointments are thicker and greasier, and are better for dry or flaky areas of skin. The amount of cream or ointment you need to use is sometimes measured in fingertip units.

This is the amount you can squeeze onto the end of your finger. For children, the right amount of cream or ointment depends on their age. A doctor or pharmacist can advise you.

Skin creams can dry onto your clothes and bedding. This makes them more likely to catch fire. Avoid naked flames. If you need to use a dressing, like a bandage or plaster, wait at least 10 minutes after putting mometasone on.

If you're treating a child, do not cover the cream or ointment with dressings or bandages. This can cause more medicine to pass through the skin and into the bloodstream, leading to a higher chance of side effects.

If your doctor has prescribed it to treat very severe nappy rash, ask them how much to use and how long to use it for. Once your skin starts getting better, do not stop using mometasone suddenly. Speak to your doctor, who might tell you to gradually reduce your dose or give you a milder steroid cream or ointment to use until you stop completely. Most people only need to use mometasone skin treatments for a short time.

Stop as soon as your skin is better. You will usually only use it for a few days. Children must not use mometasone skin treatments for more than 5 days, unless their doctor says to use it for longer. Only use the cream or ointment for longer than 5 days if your doctor tells you to. Speak to your doctor if your skin gets worse or does not get better within 14 days of using mometasone skin treatments. If you forget to use your mometasone, do not worry. In this case, skip the missed dose and apply the next one at the usual time.

Mometasone skin products are unlikely to cause any side effects if you follow the instructions. Some people get a burning or stinging feeling for a few minutes when they put mometasone on their skin.

Ask your doctor if you need to carry a steroid emergency card. Serious side effects are rare. Using mometasone for a long time can make your skin thinner or cause stretch marks.

Stretch marks are likely to be permanent, but they usually fade over time. In very rare cases, using mometasone for a long time can slow down the normal growth of children and teenagers.

Your child's doctor will monitor their height and weight carefully for as long as they're using this medicine. This will help them to notice if your child's growth is being affected and change their treatment if needed.

Even if your child's growth slows down, it does not seem to have much effect on their overall adult height. Talk to your doctor if you're worried. They will be able to explain the benefits and risks of your child using mometasone. It happens rarely but it is possible to have a serious allergic reaction anaphylaxis to mometasone. These are not all the side effects of mometasone. For a full list see the leaflet inside your medicines packet.

Mometasone skin treatments are not normally recommended if you're pregnant. Only use mometasone if your doctor or dermatologist skin specialist prescribes it and is supervising your treatment.

They will be able to explain the benefits and risks of using mometasone. If you're using mometasone on your breasts, wash off any cream or ointment from your breasts, then wash your hands before feeding your baby. It's usually better to use cream rather than ointment when breastfeeding, as it's easier to wash off. For more information about how mometasone for skin might affect you and your baby during pregnancy, read this leaflet about steroid creams and ointments on the Best Use of Medicines in Pregnancy BUMPs website.

Other medicines are unlikely to affect the way mometasone skin treatments work. There's very little information about taking herbal remedies and supplements while using mometasone. Ask a pharmacist for advice. Tell your doctor or pharmacist if you're taking any other medicines, including herbal medicines, vitamins or supplements. Mometasone is a steroid also called a corticosteroid.

Steroids help to reduce swelling inflammation in the skin and other parts of the body. Skin gets inflamed when an allergic reaction or irritation causes chemicals to be released in the skin.

These make your blood vessels widen and your irritated skin becomes red, swollen, itchy and painful. This reduces any swelling, redness and itching. Speak to your doctor if there if your skin does not get better after 14 days, or if your skin gets worse at any time. For long-term skin problems, such as eczema and psoriasis, you may need to use mometasone for 1 or 2 weeks, or sometimes for longer.

Do not use mometasone on your face for more than 5 days, unless your doctor tells you this is OK. If your symptoms get worse or if they have not improved after 14 days after 5 days for a childask your doctor for further advice. Once your skin is better, you can use an emollient moisturising treatment to keep it from becoming inflamed again. If you need treatment for a long time, your doctor may decide you need to use a milder cream or ointment. Talk to your doctor before stopping treatment if you've been using mometasone for a long time.

They may tell you to gradually use less of it, and use it less often, before you stop completely. This reduces the chance of your symptoms coming back. Using mometasone for a long time without stopping can mean some of the medicine gets into your bloodstream.

If you have been using mometasone for a long time, your doctor may tell you to gradually reduce the amount you use, or use a milder steroid, before stopping completely.

The skin on your face is delicate. If a doctor has said you can use it on your face, do not use it for more than 5 days. Steroids like mometasone reduce swelling inflammation in your skin to help manage your symptoms. They do not cure eczema. If you feel your symptoms are getting worse after using mometasone, it's important to tell a doctor. When you stop using mometasone, skin conditions like eczema and psoriasis can flare up again.

You can avoid this by gradually reducing the amount you put on, and how often you use it. Your doctor can tell you how to do this. But tell the doctor or nurse that you're using mometasone skin treatments so they can give the vaccine in an untreated area of your skin. If you're using steroid medicines such as mometasone, your adrenal glands may not make as much of some of the hormones your body needs such as cortisol known as the stress hormone.

This is known as adrenal insufficiency. This card is the size of a credit card and fits in your wallet or purse. If you need any medical or dental treatment, or are having surgery or an invasive procedure, show your steroid emergency card to your doctor or dentist. This is important so they know you're having steroid treatment and can give you extra steroids as needed. However, speak to a pharmacist or your doctor if you are trying to get pregnant. Mometasone does not affect any type of contraception, including the combined pill and emergency contraception.

Page last reviewed: 14 October Next review due: 14 October Mometasone for skin - Brand name: Elecon On this page About mometasone for skin Key facts Who can and cannot use mometasone for skin How and when to use mometasone for skin Side effects Pregnancy and breastfeeding Cautions with other medicines Common questions about mometasone for skin.

About mometasone for skin Mometasone skin treatments are used to treat itching, swollen and irritated skin. They come as: creams ointments scalp lotions They are stronger than some other treatments.

It also comes as an inhaler and a nasal spray. Read about: mometasone inhalers — for asthma mometasone nasal sprays — for allergic rhinitis, hay fever and nasal polyps.

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    Wash and dry your hands. This chronic inflammatory skin disorder is generally confined to areas of the head and trunk where sebaceous glands are most prominent. Other options include application of a moderate- to mid-potency topical corticosteroid in an ointment base.

Certain medicines should not be used at or around the time of kidney food or eating good types of food since interactions may expect. Using alcohol or tobacco with certain medicines may also comes interactions to occur. Soap with your healthcare professional the use of your physician with food, alcohol, or tobacco. The west of other medical problems may affect the use of this medication.

Make sure you tell your return if you have any other medical specialists, especially:This section provides information on the active use of a number of distributors that contain benzoyl assistant.

Background: Facial seborrheic dermatitis SDa chronic inflammatory skin condition, can impact quality of life, and relapses can be frequent. Three broad categories of agents are used to treat SD: antifungal agents, keratolytics, and corticosteroids.

Topical therapies are the first line of defense in treating this condition. Objective: Our objective was to critically review the published literature on topical treatments for facial SD. We then conducted both a critical analysis of the selected studies by grading the evidence and a qualitative comparison of results among and within studies.

Results: A total of 32 studies were eligible for inclusion, encompassing 18 topical treatments for facial SD. Pimecrolimus, the focus of seven of the 32 eligible studies, was the most commonly studied topical treatment. Ciclopirox olamine, ketoconazole, lithium gluconate and succinateand tacrolimus are also strongly recommended level A recommendations topical treatments for facial SD, as they are consistently effective across high-quality trials randomized controlled trials.

Abstract Background: Facial seborrheic dermatitis SDa chronic inflammatory skin condition, can impact quality of life, and relapses can be frequent. Publication types Review Systematic Review.

They can help with different types of eczema (including atopic dermatitis and seborrheic dermatitis) and psoriasis. Mometasone skin treatments are available on. Promiseb ®, desonide, mometasone furoate, and pimecrolimus were found to be effective topical treatments for facial SD, as they had the lowest recurrence. Promiseb ®, desonide, mometasone furoate, and pimecrolimus were found to be effective topical treatments for facial SD, as they had the lowest recurrence. Low-potency topical corticosteroids, such as hydrocortisone, desonide, and mometasone furoate, have shown to be efficacious on the face. between psoriasis and seborrheic dermatitis. The diagnosis of psoriasis was confirmed morphologically. Mometasone furoate lotion was selected for topical. Topical anti-inflammatory drugs included mild steroids hydrocortisonestrong steroids methylprednisolone, betamethasone, clobetasol, amcinonide, mometasone and fluocinoloneand calcineurin inhibitors pimecrolimus and tacrolimus. Benzoyl peroxide washes are also helpful in controlling seborrhea of the trunk. Skin creams can dry onto your clothes and bedding.

Topical anti-inflammatory agents for seborrhoeic dermatitis of the face or scalp. Cochrane Database Syst Rev. In adults with seborrheic dermatitis of the scalp or face, do anti-inflammatory drugs that are used topically applied to the skin reduce symptoms? Seborrheic dermatitis is a fairly common rash, an inflammation of the skin that causes redness, scaling or flaking, or itching. It mostly affects skin on the scalp as dandruff , face, chest and at joints e.

Treatments include topical drugs that are applied to affected areas of skin e. The reviewers did a systematic review , searching for studies that were published up to September They found 36 randomized controlled trials with people. Topical anti-inflammatory drugs included mild steroids hydrocortisone , strong steroids methylprednisolone, betamethasone, clobetasol, amcinonide, mometasone and fluocinolone , and calcineurin inhibitors pimecrolimus and tacrolimus.

People were treated for 4 weeks or less. These drugs were compared with placebo , each other, or other treatments, including azoles ketoconazole, metronidazole and miconazole.

Compared with placebo :. Strong and mild steroids did not differ for completely resolving symptoms, reducing scaling and itching, or for adverse effect rates in 2 to 3 trials. In people with seborrheic dermatitis of the face or scalp, use of topical steroids for 4 weeks or less reduces symptoms more than placebo but has a similar effect to calcineurin inhibitors or azoles.

Mild or strong steroids vs placebo. Symptoms cleared in about 22 more people out of from as few as 7 to as many as 38 out of This means that the differences could simply be due to chance rather than due to the different treatments. Help us to continue to provide direct and easy access to evidence-based information on health and social conditions to help you stay healthy, active and engaged as you grow older. Donate Today. We just need your email, then we'll add you to the list!

Cancel Subscribe. Toggle navigation McMaster University info mcmasteroptimalaging. Back Evidence Summary. What is an Evidence Summary? Key messages from scientific research that's ready to be acted on Got It, Hide this. In people with seborrheic dermatitis of the face or scalp, short-term use of topical steroids reduces symptoms Kastarinen H, Oksanen T, Okokon EO, et al.

Review question In adults with seborrheic dermatitis of the scalp or face, do anti-inflammatory drugs that are used topically applied to the skin reduce symptoms? Background Seborrheic dermatitis is a fairly common rash, an inflammation of the skin that causes redness, scaling or flaking, or itching.

How the review was done The reviewers did a systematic review , searching for studies that were published up to September People in the trials had seborrheic dermatitis of the scalp or face. What the researchers found Compared with placebo : steroids completely resolved symptoms in more people; strong steroids reduced skin redness and scaling in 3 trials; strong steroids reduced itching in 2 trials but not in a 3 rd trial; and steroids had similar adverse effect rates across 3 trials e.

Compared with calcineurin inhibitors, steroids: completely resolved symptoms in a similar proportion of people; and had fewer adverse effects e. Compared with azoles, steroids: completely resolved symptoms in a similar proportion of people; reduced skin redness, scaling and itching in some trials but not in others; and had similar rates of adverse effects e.

Conclusions In people with seborrheic dermatitis of the face or scalp, use of topical steroids for 4 weeks or less reduces symptoms more than placebo but has a similar effect to calcineurin inhibitors or azoles. View Clinician article. Related Topics Skin conditions. Placebo A harmless, inactive, and simulated treatment. Randomized controlled trials Studies where people are assigned to one of the treatments purely by chance.

Systematic review A comprehensive evaluation of the available research evidence on a particular topic. Topical drug A drug that is applied to a specific area on the skin or other surface on the body, such as the eye. It can be a cream, lotion, gel, ointment, patch, or some other form.

Related Evidence Summaries Higher density foam mattresses and sheepskins reduce risk of pressure ulcers. Related Web Resources Treating pressure ulcers: New evidence, continued uncertainty. Gauze dressings should not be used to treat pressure ulcers bed sores.

Other options include alginate dressings, hydrogel dressings, and negative pressure wound therapy. More evidence is needed about which options are best to improve pain and reduce complications. Research should measure outcomes that matter to patients and carers as well as health professionals. Creams containing azelaic acid or the antibiotic metronidazole may help with your rosacea symptoms. Hives are raised, itchy bumps that are red in colour.

Hives usually appear suddenly and last a few days to a week or two. Treatment can include antihistamines, oral steroids, and avoiding allergens or other triggers. See a doctor immediately if your hives appear with serious allergy symptoms such as trouble breathing, vomiting or passing out.

They are not a substitute for advice from your own health care professional. The summaries may be reproduced for not-for-profit educational purposes only. Register for free access to all Professional content Register. Want the latest in aging research? Sign up for our email alerts.



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